ACHIEVE Study Main Findings Publication*
Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): A multicentre, randomised controlled trial. Lin FR, Pike JR, Albert MS, et al. Lancet 2023 Sep 2;402(10404):786-797. doi: 10.1016/S0140-6736(23)01406-X. PMID: 37478886; PMCID: PMC10529382.
ACHIEVE Study Additional Findings/Secondary Analyses Publications*
Effects of hearing intervention on falls in older adults: Findings from a secondary analysis of the ACHIEVE randomised controlled trial. Goman AM, Tan N, Pike JR, et al. Lancet Public Health. 2025 June;10:e492-502. doi: 10.1016/S2468-2667(25)00088-X. PMID: 40441816.
Cognitive benefits of hearing intervention vary by risk of cognitive decline: A secondary analysis of the ACHIEVE trial. Pike JR, Huang AR, Reed NS, et al. Alzheimers Dement. 2025 May;21(5):e70156. doi: 10.1002/alz.70156. PMID: 40369891; PMCID: PMC12070280.
Hearing intervention, social isolation, and loneliness: A secondary analysis of the ACHIEVE randomized clinical trial. Reed NS, Chen J, Huang AR, et al. JAMA Intern Med. 2025 May 12. doi: 10.1001/jamainternmed.2025.1140. PMID: 40354063; PMCID: PMC12070280.
Effects of hearing intervention on physical activity measured by accelerometry: A secondary analysis of the ACHIEVE Study. Schrack JA, Wanigatunga AA, Glynn NW, et al. J Am Geriatr Soc. 2025 Mar 24. doi: 10.1111/jgs.19435. PMID: 40126980.
Impact of a hearing intervention on the levels of leisure-time physical activity and T.V. viewing in older adults: Results from a secondary analysis of the ACHIEVE trial. Martinez-Amezcua P, Zhang W, Assi S, et al. J Gerontol A Biol Sci Med Sci. 2025 May 5;80(6):glaf033. PMID: 39953975.
Effect of hearing intervention on communicative function: A secondary analysis of the ACHIEVE randomized controlled trial. Sanchez VA, Arnold ML, Garcia Morales EE, et al. J Am Geriatr Soc. 2024 Dec;72(12):3784-3799. doi:10.1111/jgs.19185. PMID: 39266468; PMCID: PMC11637286.
A Hearing Intervention and Health-Related Quality of Life in Older Adults: A Secondary Analysis of the ACHIEVE Randomized Clinical Trial. Huang AR, Morales EG, Arnold ML, et al. JAMA Netw Open. 2024 Nov 4;7(11):e2446591. doi:10.1001/jamanetworkopen.2024.46591. PMID: 39570588; PMCID: PMC11582982.
Effect of Hearing Intervention Versus Health Education Control on Fatigue: A Secondary Analysis of the ACHIEVE Study. Bessen SY, Zhang W, Huang AR, et al. J Gerontol A Biol Sci Med Sci. 2024 Nov 1;79(11):glae193. doi:10.1093/gerona/glae193. PMID: 39093692; PMCID: PMC11402025.
ACHIEVE Baseline Publications*
Cross-sectional associations of peripheral hearing, brain imaging, and cognitive performance with speech-in-noise performance: The Aging and Cognitive Health Evaluation in Elders Brain Magnetic Resonance Imaging ancillary study. Jiang K, Albert MS, Coresh J, et al. Am J Audiol. 2024 Sep 3;33(3):683-694. doi: 10.1044/2024_AJA-23-00108. PMID: 38748919; PMCID: PMC11427419.
Hearing impairment and physical activity and physical functioning in older adults: Baseline results from the ACHIEVE trial. Cai Y, Martinez-Amezcua P, Betz JF, et al. J Gerontol A Biol Sci Med Sci. 2024 Jul 1;79(7):glae117. doi: 10.1093/gerona/glae117. PMID: 38695059; PMCID: PMC11170292.
Depression and health-related quality of life among older adults with hearing loss in the ACHIEVE Study. Huang AR, Reed NS, Deal JA,et al. J Appl Gerontol. 2024 May;43(5):550-561. doi: 10.1177/07334648231212291. PMID: 38016096; PMCID: PMC10981564.
Recruitment and baseline data of the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) study: A randomized trial of a hearing loss intervention for reducing cognitive decline. Reed NS, Gravens-Mueller L, Huang AR, et al. Alzheimers Dement (N Y). 2024 Feb 14;10(1):e12453. doi: 10.1002/trc2.12453. PMID: 38356470; PMCID: PMC10865776.
Loneliness and social network characteristics among older adults with hearing loss in the ACHIEVE study. Huang AR, Reed NS, Deal JA, et al. J Gerontol A Biol Sci Med Sci. 2024 Feb 1;79(2):glad196. doi: 10.1093/gerona/glad196. PMID: 37578190; PMCID: PMC10809043.
Description of the baseline audiologic characteristics of the participants enrolled in the Aging and Cognitive Health Evaluation in Elders study. Sanchez VA, Arnold ML, Betz JF, et al. Am J Audiol. 2024 Jan 2;33(1):1-17. doi: 10.1044/2023_AJA-23-00066. PMID: 38166200; PMCID: PMC11001432.
Study Design and ACHIEVE Pilot Study Publications*
Hearing loss and cognition: A protocol for ensuring speech understanding before neurocognitive assessment. Kolberg ER, Morales EEG, Thallmayer TW, et al. Alzheimers Dement. 2024 Mar;20(3):1671-1681. doi: 10.1002/alz.13552. PMID: 38081140; PMCID: PMC10947954.
Development, assessment, and monitoring of audiologic treatment fidelity in the aging and cognitive health evaluation in elders (ACHIEVE) randomised controlled trial. Arnold ML, Haley W, Lin FR, et al. Int J Audiol. 2022 Sep;61(9):720-730. doi: 10.1080/14992027.2021.1973126. PMID: 34533430; PMCID: PMC11992692.
The Hearing Intervention for the Aging and Cognitive Health Evaluation in Elders Randomized Control Trial: Manualization and Feasibility Study. Sanchez VA, Arnold ML, Reed NS, et al. Ear Hear. 2020 Sep/Oct;41(5):1333-1348. doi: 10.1097/AUD.0000000000000858. PMID: 32251012; PMCID: PMC10436703.
Hearing treatment for reducing cognitive decline: Design and methods of the Aging and Cognitive Health Evaluation in Elders randomized controlled trial. Deal JA, Goman AM, Albert MS, et al. Alzheimers Dement (N Y). 2018 Oct 5;4:499-507. doi: 10.1016/j.trci.2018.08.007. PMID: 30364572; PMCID: PMC6197326.
A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study. Deal JA, Albert MS, Arnold M, et al. Alzheimers Dement (N Y). 2017 Jun 21;3(3):410-415. doi: 10.1016/j.trci.2017.06.003. PMID: 29067347; PMCID: PMC5651440.
* Publications link out to the official journal articles. The PubMed Central free versions can be accessed here.