ACHIEVE Study Main Findings Publication*
Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): A multicentre, randomised controlled trial. Lin FR, Pike JR, Albert MS, et al. Lancet 2023 Sep 2;402(10404):786-797. doi: 10.1016/S0140-6736(23)01406-X. PMID: 37478886; PMCID: PMC10529382.
ACHIEVE Study Additional Findings/Secondary Analyses Publications*
Effects of hearing intervention on physical function: A secondary analysis of the ACHIEVE study. Deal JA, Zhang W, Jiang K, et al. PLoS One. 2026 Apr 29;21(4):e0347500. doi: 10.1371/journal.pone.0347500. PMID: 42054408; PMCID: PMC13127907.
Patient-centered hearing intervention leads to positive outcomes: The association of hearing technology with daily hearing aid usage and listening goals in the Aging and Cognitive Health Evaluation in Elders Study. Sanchez VA, Garcia Morales EE, Arnold ML, et al. Am J Audiol. 2026 Apr 27:1-18. doi: 10.1044/2026_AJA-25-00229. PMID: 42044054.
Hearing intervention, social isolation, and loneliness: A secondary analysis of the ACHIEVE randomized clinical trial. Reed NS, Chen J, Huang AR, et al. JAMA Intern Med. 2025 Jul 1;185(7):797-806. doi: 10.1001/jamainternmed.2025.1140. PMID: 40354063; PMCID: PMC12070280.
Effects of hearing intervention on physical activity measured by accelerometry: A secondary analysis of the ACHIEVE Study. Schrack JA, Wanigatunga AA, Glynn NW, et al. J Am Geriatr Soc. 2025 Jun; 73(6):1762-1771. doi: 10.1111/jgs.19435. PMID: 40126980; PMCID: PMC12213142.
Effects of hearing intervention on falls in older adults: Findings from a secondary analysis of the ACHIEVE randomised controlled trial. Goman AM, Tan N, Pike JR, et al. Lancet Public Health. 2025 June;10:e492-502. doi: 10.1016/S2468-2667(25)00088-X. PMID: 40441816; PMCID: PMC12203021.
Cognitive benefits of hearing intervention vary by risk of cognitive decline: A secondary analysis of the ACHIEVE trial. Pike JR, Huang AR, Reed NS, et al. Alzheimers Dement. 2025 May;21(5):e70156. doi: 10.1002/alz.70156. PMID: 40369891; PMCID: PMC12070280.
Impact of a hearing intervention on the levels of leisure-time physical activity and T.V. viewing in older adults: Results from a secondary analysis of the ACHIEVE trial. Martinez-Amezcua P, Zhang W, Assi S, et al. J Gerontol A Biol Sci Med Sci. 2025 May 5;80(6):glaf033. PMID: 39953975; PMCID: PMC13032009.
Effect of hearing intervention on communicative function: A secondary analysis of the ACHIEVE randomized controlled trial. Sanchez VA, Arnold ML, Garcia Morales EE, et al. J Am Geriatr Soc. 2024 Dec;72(12):3784-3799. doi:10.1111/jgs.19185. PMID: 39266468; PMCID: PMC11637286.
A Hearing Intervention and Health-Related Quality of Life in Older Adults: A Secondary Analysis of the ACHIEVE Randomized Clinical Trial. Huang AR, Morales EG, Arnold ML, et al. JAMA Netw Open. 2024 Nov 4;7(11):e2446591. doi:10.1001/jamanetworkopen.2024.46591. PMID: 39570588; PMCID: PMC11582982.
Effect of Hearing Intervention Versus Health Education Control on Fatigue: A Secondary Analysis of the ACHIEVE Study. Bessen SY, Zhang W, Huang AR, et al. J Gerontol A Biol Sci Med Sci. 2024 Nov 1;79(11):glae193. doi:10.1093/gerona/glae193. PMID: 39093692; PMCID: PMC11402025.
ACHIEVE Baseline Publications*
Cross-sectional associations of peripheral hearing, brain imaging, and cognitive performance with speech-in-noise performance: The Aging and Cognitive Health Evaluation in Elders Brain Magnetic Resonance Imaging ancillary study. Jiang K, Albert MS, Coresh J, et al. Am J Audiol. 2024 Sep 3;33(3):683-694. doi: 10.1044/2024_AJA-23-00108. PMID: 38748919; PMCID: PMC11427419.
Hearing impairment and physical activity and physical functioning in older adults: Baseline results from the ACHIEVE trial. Cai Y, Martinez-Amezcua P, Betz JF, et al. J Gerontol A Biol Sci Med Sci. 2024 Jul 1;79(7):glae117. doi: 10.1093/gerona/glae117. PMID: 38695059; PMCID: PMC11170292.
Depression and health-related quality of life among older adults with hearing loss in the ACHIEVE Study. Huang AR, Reed NS, Deal JA,et al. J Appl Gerontol. 2024 May;43(5):550-561. doi: 10.1177/07334648231212291. PMID: 38016096; PMCID: PMC10981564.
Recruitment and baseline data of the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) study: A randomized trial of a hearing loss intervention for reducing cognitive decline. Reed NS, Gravens-Mueller L, Huang AR, et al. Alzheimers Dement (N Y). 2024 Feb 14;10(1):e12453. doi: 10.1002/trc2.12453. PMID: 38356470; PMCID: PMC10865776.
Loneliness and social network characteristics among older adults with hearing loss in the ACHIEVE study. Huang AR, Reed NS, Deal JA, et al. J Gerontol A Biol Sci Med Sci. 2024 Feb 1;79(2):glad196. doi: 10.1093/gerona/glad196. PMID: 37578190; PMCID: PMC10809043.
Description of the baseline audiologic characteristics of the participants enrolled in the Aging and Cognitive Health Evaluation in Elders study. Sanchez VA, Arnold ML, Betz JF, et al. Am J Audiol. 2024 Jan 2;33(1):1-17. doi: 10.1044/2023_AJA-23-00066. PMID: 38166200; PMCID: PMC11001432.
Study Design and ACHIEVE Pilot Study Publications*
Hearing loss and cognition: A protocol for ensuring speech understanding before neurocognitive assessment. Kolberg ER, Morales EEG, Thallmayer TW, et al. Alzheimers Dement. 2024 Mar;20(3):1671-1681. doi: 10.1002/alz.13552. PMID: 38081140; PMCID: PMC10947954.
Development, assessment, and monitoring of audiologic treatment fidelity in the aging and cognitive health evaluation in elders (ACHIEVE) randomised controlled trial. Arnold ML, Haley W, Lin FR, et al. Int J Audiol. 2022 Sep;61(9):720-730. doi: 10.1080/14992027.2021.1973126. PMID: 34533430; PMCID: PMC11992692.
The Hearing Intervention for the Aging and Cognitive Health Evaluation in Elders Randomized Control Trial: Manualization and Feasibility Study. Sanchez VA, Arnold ML, Reed NS, et al. Ear Hear. 2020 Sep/Oct;41(5):1333-1348. doi: 10.1097/AUD.0000000000000858. PMID: 32251012; PMCID: PMC10436703.
Hearing treatment for reducing cognitive decline: Design and methods of the Aging and Cognitive Health Evaluation in Elders randomized controlled trial. Deal JA, Goman AM, Albert MS, et al. Alzheimers Dement (N Y). 2018 Oct 5;4:499-507. doi: 10.1016/j.trci.2018.08.007. PMID: 30364572; PMCID: PMC6197326.
A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study. Deal JA, Albert MS, Arnold M, et al. Alzheimers Dement (N Y). 2017 Jun 21;3(3):410-415. doi: 10.1016/j.trci.2017.06.003. PMID: 29067347; PMCID: PMC5651440.
* Publications link out to the official journal articles. The PubMed Central free versions can be accessed here.